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Turning PET Plastic Into Paracetamol With This One Bacterial Trick


Over the course of evolution microorganisms have evolved pathways to break down many materials. The challenge with the many materials that we humans have created over just the past decades is that we cannot wait for evolution to catch up, ergo we have to develop such pathways ourselves. One such example is demonstrated by [Nick W. Johnson] et al. with a recent study in Nature Chemistry that explicitly targets PET plastic, which is very commonly used in plastic bottles.

The researchers modified regular E. coli bacteria to use PET plastic as an input via Lossen rearrangement, which converts hydroxamate esters to isocyanates, with at the end of the pathway para-aminobenzoate (PABA) resulting, which using biosynthesis created paracetamol, the active ingredient in Tylenol. This new pathway is also completely harmless to the bacterium, which is always a potential pitfall with this kind of biological pathway engineering.

In addition to this offering a potential way to convert PET bottles into paracetamol, the researchers note that their findings could be very beneficial to studies targeting other ‘waste’ products from biological pathways.

Thanks to [DjBiohazard] for the tip.


hackaday.com/2025/07/08/turnin…




A Ukrainian airstrike targeted a gathering point of Russian UAVs and personnel in occupied Luhansk region, hitting forces and equipment.


Save 50% on Disperser magic all-pass filter by Kilohearts rekkerd.org/kilohearts-dispers…

#AAX #AU #Filter #kiloHearts #Sale #VST



@classicalmusic
Beethoven - Violin Sonata No. 3 in E-Flat Major, Op. 12 No. 3

Yehudi Menuhin, violin -
Wilhelm Kempff, piano

(studio recording, 1970)

youtube.com/watch?v=QRP0FJtFDc…

#music #classic #chambermusic #history



Positionspapier: AfD im Panikmodus wegen der Verbotsdebatte
volksverpetzer.de/analyse/posi…



Turning PET Plastic Into Paracetamol With This One Bacterial Trick

hackaday.com/2025/07/08/turnin…



Macron a Westminster, 'europei non abbandoneranno mai Kiev' - Ultima ora - Ansa.it
https://www.ansa.it/sito/notizie/topnews/2025/07/08/macron-a-westminster-europei-non-abbandoneranno-mai-kiev_e6eb9c3c-1eec-46b7-a4a7-4dd399a9bc88.html?utm_source=flipboard&utm_medium=activitypub

Pubblicato su ANSA Ultima ora @ansa-ultima-ora-AgenziaAnsa





Frontière franco-espagnole : ouverture d'une cellule d'échange de renseignements sur l’immigration à Biriatou
infomigrants.net/fr/post/65640…
"La cellule départementale d’échange de renseignements à la frontière franco-espagnole a ouvert la semaine dernière à Biriatou, ville frontalière avec l'Espagne, devenue l'un des points de passage de migrants vers la France. Cette



Morreu Filipe Guerra, tradutor premiado das grandes obras russas mag.sapo.pt/showbiz/artigos/mo…


Le friggitrici ad aria più ghiotte in offerta per l'Amazon Prime Day
https://www.wired.it/gallery/amazon-prime-day-friggitrici-aria/?utm_source=flipboard&utm_medium=activitypub

Pubblicato su Wired Consiglia @wired-consiglia-WiredItalia



En Alsace, chez BDR Thermea, l’apolitisme de FO sert d’estrade au RN
rapportsdeforce.fr/classes-en-…
"À Mertzwiller, le soutien aux salariés de BDR Thermea a tourné à l’affrontement syndical. Alors qu’un député RN s’est invité à la tribune avec la bénédiction de FO et de la CFE-CGC, les syndicalistes opposés à l’extrême droite ont été […]
L’article En Alsace, chez BDR Thermea, l’apolitisme de FO sert


@classicalmusic
Ferdinand Ries - Piano Sonata No. 14, Op. 11, No. 2

Susan Kagan, piano

youtube.com/watch?v=vRHsP5Yx-t…

#music #classic #piano



t.me/warriorsukrainian/57515
⛔️⚠️Seven more Ukrainian children were rescued from the temporarily occupied territories as part of the Bring Kids Back UA initiative. The families were subjected to pressure from the occupiers, forced to take (PHOTOS and more) #Ukraine #Mastodon #Germany #France #Italy #OSCE #PACE #CoE #SouthKorea #Press #News #Taiwan #Media #Japan #USA #US #UK #EU #NATO #UnitedStates #UnitedKingdom
#EuropeanUnion #russiaUkraineWar
#11yrInvasionofUkraine
#RussiaIsATerroristState


Here Are All The Best Prime Day Home Deals
https://www.huffpost.com/entry/best-prime-day-home-deals_l_686d35b0e4b052503287203d?utm_source=flipboard&utm_medium=activitypub

Posted into Shopping @shopping-huffingtonpost



Mein UAS client läuft endlich so weit :3

Telekom hat irgendwie voll lust ein reinvite zu machen. das hat mich noch ein paar fehler finden lassen.

nun muss ich ihm noch beibringen, von selbst aufzulegen.

und ich hab noch ein paar andre punkte. aber der haupt brocken ist geschafft :3

in reply to Moppi

was ist das für ein Tool, wenn ich fragen darf?
in reply to e_es

@e_es das ist sngrep
Das ist bei den meisten distros im Katalog zu finden :3

Es erleichtert ungemein das arbeiten :3

@e_es


Europeans will never abandon Ukraine, Macron said, adding that France and the UK must work together to protect the international order established in 1945. “We will fight until the last moment to ensure peace in Ukraine,” he stated.
Questa voce è stata modificata (2 mesi fa)

JonChevreau reshared this.




💡 Microsoft Edge migliora la velocità e carica i contenuti in meno di 300 millisecondi

gomoot.com/microsoft-edge-migl…

#blog #chrome #edge #microsoft #news #picks #tech #tecnologia #webui



Mariia Buhaiova trovata morta a Carovigno: la giovane trovata impiccata liberoreporter.it/2025/07/cron…


A Marco Rubio Impostor is Using AI Voice To Call High-Level Officials news.slashdot.org/story/25/07/…




#TaxTheRich in #Germany epetitionen.bundestag.de/petit…
Leute, registriert euch bei der Bundestags-Petitionsseite, bitte 🙏 und unterschreibt.
Denn so kann es doch nicht weitergehen - die #ArmReichSchere klafft immer weiter auf und zu viele sind schon in den Abgrund gestürzt. Wir müssen das aufhalten und korrigieren!
Questa voce è stata modificata (2 mesi fa)

reshared this


in reply to 🍂 Grumpers 🍁

Das Video zeigt eine Gruppe von bewaffneten Polizisten in Tarnuniformen und Schutzkleidung, die in Los Angeles, USA, auf einer Straße stehen. Sie tragen Ausrüstung wie Schutzwesten, Helme und Gasmasken. Im Hintergrund sind Militärfahrzeuge zu sehen, einschließlich eines gepanzerten Fahrzeugs. Text auf dem Bild lautet "Hollywoodreife Szenen in Los Angeles" und "PLÖTZLICHER MILITÄRAUFMARSCH," was auf eine plötzliche militärische Präsenz hinweist. Die Polizisten sind in einer Formation aufgestellt, einige stehen vor einem gepanzerten Fahrzeug, während andere auf einem gepanzerten Fahrzeug stehen. Ein weiterer Text lautet "Militärfahrzeuge und eine boritierte Einheit durchkämmen den MacArthur Park," was darauf hinweist, dass die Einheit den MacArthur Park durchkämmt. Ein weiterer Text lautet "Vermummte Soldaten in Gasmasken und Helikopter," was auf die Anwesenheit von verkleideten Soldaten und Helikoptern hinweist. Ein Helikopter mit der Kennung "N914KB" ist zu sehen, der über eine Stadtlandschaft fliegt. Der Text "wo sonst Familien ihre Freizeit genießen" und "Wir dachten, was ist das? Sieht aus wie ein Kriegsgebiet" beschreibt die Situation als ungewöhnlich und bedrohlich.

Bereitgestellt von @altbot, privat und lokal generiert mit Ovis2-8B

🌱 Energieverbrauch: 0.658 Wh




_"No Evidence" of Epstein Blackmail Operation Not Surprising_

The more "it doesn't make sense," the more one should suspect behind-the-scenes shenanigans.

FTA: When institutions and powerful individuals operate for long periods without scrutiny, they may be tempted to commit such outrageously corrupt acts that disclosing them to the people becomes an insurmountably difficult task.

For years there has been a lot of consternation about the refusal of federal agencies such as the CIA and FBI to disclose what they know about Jeffrey Epstein (as well as about the assassination of JFK, the 9/11 terrorist attacks, the murder of Seth Rich, and countless other stories). Guys like me have also noticed how the U.S. government, including Congress, can’t ever quite seem to get to the bottom of the origin of SARS-CoV-2.

The truth of these stories carries incalculable liabilities—liabilities that would call into question whether the involved institutions should be allowed to continue existing.

Disclosing the truth could also instantly demolish the persistent naïveté that enables most people to maintain their allegiance to their governments and to believe the endless train of BS that we are told every day about everything.

I have experience with big liability cases. For a long time I investigated the mysterious deaths of Mary Mahoney on July 6, 1997 in Georgetown and Seth Rich on July 10, 2016 in the Bloomingdale neighborhood of D.C. The circumstances of both deaths strongly raise the suspicion of a political motive, but both were nevertheless chalked up to “botched robberies” by the Metropolitan Police.

Someone with power doesn’t want either death elucidated, and I was advised that pursuing my investigations would not only be frustrating and fruitless, but hazardous for my health.

thefocalpoints.com/p/no-eviden…


in reply to ScoWer22

@ScoWer22 #Rednex ... 😂😂😂 Oh, wait! That's a Swedish group, or was one. But Annika Ljungberg is/was a singer of them.


Quelqu’un saurait expliquer comment j’ai pu survivre 43 ans sans connaître l’existence de l’Ovomaltine Crunchy ?!
:CattoLooove:
#Food #Nourriture

reshared this



#FromOuterspace
L’interdiction d’une piscine suisse aux non-résidents “crée des remous” jusqu’en France
courrierinternational.com/arti…
"Le maire de Porrentruy, commune suisse proche de la France, a déclenché une polémique des deux côtés de la frontière en interdisant l’accès à sa piscine aux non-résidents. La mesure fait suite à des débordements et cible les Français, explique


💡 Thunderbird 140 Eclipse porta il dark mode e la compatibilità nativa con Exchange

gomoot.com/thunderbird-140-ecl…

#blog #client #eclipse #email #ews #exchange #gartuito #gratis #mozilla #news #opensource #picks #tech #tecnologia #thunderbird @mozilla



#UnoRadio #nowplaying #newmusic
Lifeguard
youtube.com/watch?v=_WOYjxIy3f…



t.me/warriorsukrainian/57508
⛔️🇷🇺Rostov. The fire occurred in a warehouse with household appliances. Explosions were heard in the warehouse (PHOTOS, VIDEO) #Ukraine #Mastodon #NukesForUkraine #Germany #France #Italy #OSCE #PACE #CoE #SouthKorea #Press #News #Taiwan #Media #Japan #USA #US #UK #EU #NATO #UnitedStates #UnitedKingdom
#EuropeanUnion #russiaUkraineWar
#11yrInvasionofUkraine
#RussiaIsATerroristState #TrumpIsARussianAsset



😟 Trump is working on regime change in Europe — fact, not conspiracy theory.
CAROLINE DE GRUYTER:
"This American administration increasingly considers elections in Europe — recently in Romania and Poland, and soon in the Netherlands, the Czech Republic and, as some speculate, France too — as an opportunity to get European countries governed by far-right leaders with Trumpian agendas."
euobserver.com/eu-and-the-worl…

in reply to Jesse

The image shows a screenshot of a Reddit post and a reply. The post, made 10 hours ago, is from a user with a blue circular profile picture featuring a cartoonish character. The text reads: "the official elden ring discord has a spot to put recommendations, i'm going to add this there, you should do the same. This is a great idea." Below the text is a blue hyperlink to the official Elden Ring Discord invite page: "discord.com/invite/eldenring." The post has received 710 upvotes.

The reply, also made 10 hours ago, is from a user with a blue circular profile picture. The text reads: "elden ring midcord." This reply has received -379 downvotes. The layout of the Reddit interface is visible, with options to reply, upvote, and downvote, as well as a timestamp and the number of upvotes and downvotes.

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#Ferrari, #Zapelloni furioso: «#Vigna, manca chiarezza. E #Vasseur vede un altro film...» formula1.it/news/25800/1/ferra…


La Meloni vuole incolpare le opposizioni per gli sprechi della destra? gayburg.com/2025/07/la-meloni-…


Indignació i malestar a les xarxes pel tractament que TV3 ha fet de l’incendi de Paüls

larepublica.cat/noticies/indig…



united states cumulative measles cases in 2025: 1,277 (at least)
highest count in 33 years

really can't stand the anti-science trend in the united states right now





Economist: Politische Machtspiele in Kiew werden heftig de.rt.com/europa/250065-econom… In der ukrainischen Führung herrschen Chaos und Intrigen, berichtet die Zeitung The Economist. Im Zentrum der Machtspiele steht Andrei Jermak, der Leiter des Präsidentenbüros. Bereits mehrmals versuchte er, Geheimdienstchef Kirill Budanow zu stürzen. #news #press


Conflitto d’interessi e libertà dei giornalisti, l’Ue bacchetta l’Italia nel Rapporto 2025 sullo Stato dell’Unione articolo21.org/2025/07/conflit… #Articoli

Carlo Gubitosa reshared this.



so many questions...

I remember fighting over who got to lick the batter off the beaters when Ma made blue berry muffins...




On July 4, Ukrainian drones struck two buildings at the Azov Optical-Mechanical Plant. This facility produces precision optical-mechanical components for missile guidance, armored vehicle stabilizers, aviation and UAV navigation, and electronic warfare systems, KiberBoroshno reports.



Unless users take action, Android will let Gemini access third-party apps - Ars Technica

arstechnica.com/security/2025/…



If I worked on a way for people to Self-Host there own instance by resetting it up like I'd self-host at mine but then give them the device so they don't have to pay monthly fees, Do you think people would pay for that?

#Fediverse #FediverseInstance #FediverseHosting #SelfHosting

in reply to Samantha Xavia

I'm not sure how much work it would be fully but might get a Raspberry Pi or something to test the theory out but I think I could create a Mastodon Instance that can be 'portable' / be sold to people to self-host in there own home.

I want to make it easy for people to self-host, especially for those who know nothing about coding and don't have time / want to learn. The goal would be to have a 100% functional instance that would be plug-n-go no worries about typing in commands, illegal instances / users ext.

I want to be able to easily give the update code to users when it comes to update time, I think the only thing they'll have to worry about if they don't manage there own DNS is paying for the domain, but other than that it should be 100% free from my hands if they wish to run it on there own.

Who knows if I can do it but I'm thinking about testing this as I really want to help bring people to the Fediverse, and why not help people run there own servers.